Adverse Drug Reactions: What They Are, Why They Happen, and How to Stay Safe

When you take a medicine, you expect it to help—not hurt. But adverse drug reactions, unintended and harmful responses to medications at normal doses. Also known as drug side effects, they’re more common than most people realize and can range from a mild rash to life-threatening bleeding or heart problems. These aren’t just random mishaps. They’re often predictable, preventable, and tied to how your body handles certain drugs—especially when they mix with other pills, supplements, or even foods.

Take SSRIs, a class of antidepressants that affect serotonin levels. They’re widely prescribed, but they can reduce serotonin in platelets, making it harder for your blood to clot. That’s why people on SSRIs like paroxetine have a higher risk of bleeding, even from minor cuts or dental work. Or consider NSAIDs, common pain relievers like ibuprofen that can interfere with heart medications. Mixing them with blood thinners or ACE inhibitors can trigger internal bleeding, kidney damage, or heart failure. Even something as simple as diclofenac, a strong anti-inflammatory sold as Voveran SR, can cause stomach ulcers or raise blood pressure if used long-term. These aren’t edge cases—they’re documented risks backed by real patient data.

It’s not just about the drug itself. Your age, other conditions, and what else you’re taking all matter. Phenytoin, used for seizures, can weaken your bones over time. Dipyridamole and clopidogrel, both antiplatelet drugs, work differently but can overlap in side effects. Even supplements like vitamin C or herbal products can interact—sometimes in ways your doctor never warned you about. The truth is, most adverse reactions happen because we assume medications are safe on their own, without checking how they behave in combination.

What you’ll find below isn’t just a list of articles. It’s a practical guide to spotting the hidden dangers in your medicine cabinet. From how SSRIs affect clotting to why mixing heart drugs with NSAIDs can be deadly, each post breaks down real cases, real risks, and real solutions. No theory. No fluff. Just what you need to know to take your meds safely—and ask the right questions before the next prescription.